The only item duplication glitch I know about involves unequipping stuff and running during battle. It certainly wouldn't affect that. I think I recall hearing about a different, more versatile dupe glitch somewhere, but I don't know anything about the context of its application.
As long as the thing you're talking about doesn't occur during the event instruction "remove item from inventory," then no. This mod overwrites the small bit of code that zeroes out the item and quantity then and only then, and replaces it with, essentially, "reduce item quantity by one; if the result is zero, erase associated item."