Not really an issue of "do you care how good it looks".
You CAN'T fit in the English translation with that character per line limit.
It could work with platformer/simple games (and even the only game I know of, Ackman, that didn't care for that limit, had to butcher and abridge the translation horribly to make it fit at all).
Could be more difficult in RPGs, which have more text (and even then, they add lots of new text boxes to compensate).
But text-heavy dating sims/visual novels?
That's where it's a deal breaker.