| Steven Seagal in SoR2 | Cakewarden | Streets of Rage 2 | Action > Beat 'Em Up | GEN | G, S | Improvement | 1.0 | 30 Oct 2016 |
| Stepping Out | Leet Sketcher | Final Fantasy III | Role Playing | SNES | GP | Bug Fix | 1.0 | 11 Feb 2017 |
| Step Dance | HatZen08 | Final Fantasy III | Role Playing | SNES | GP | Improvement | 1.0 | 13 Feb 2013 |
| Stellar Assault Region-Free and Restoration Patch | Vague Rant | Stellar Assault | Action > Shooter | 32X | GP, O | Improvement | 1.0 | 06 Apr 2021 |
| Stella the Cat | FeliciaVal | Sonic the Hedgehog | Action > Platformer | GEN | G, L, T, GP | Improvement | 1 | 20 Jan 2011 |
| Steiner’s Thunder Slash Fix | Chronosplit | Final Fantasy IX | Role Playing | PSX | GP | Bug Fix | Final | 02 Nov 2016 |
| STED Experience | KingMike's Translations | STED: Iseki Wakusei no Yabou | Role Playing | NES | GP | Improvement | 1.0 | 11 Apr 2007 |
| Sted Easy | ded302 | STED: Iseki Wakusei no Yabou | Role Playing | NES | GP | Improvement | 1.0 | 02 Jul 2007 |
| Status Unknown | Leet Sketcher | Final Fantasy III | Role Playing | SNES | G, T | Bug Fix | 1.1 | 18 Oct 2016 |
| Status Timers Hack | Madsiur | Final Fantasy III | Role Playing | SNES | GP | Improvement | 1.0a | 16 Feb 2022 |
| Status Icon Overflow | SilentEnigma | Final Fantasy III | Role Playing | SNES | O | Bug Fix | 1.1 | 23 Apr 2022 |
| Starwing (Germany) 21mhz SuperFX | kandowontu | Star Fox | Action > Shooter | SNES | GP | Complete | 1.02 | 17 Dec 2021 |
| Starwing (Euro Rev 1) 21mhz SuperFX Speed | kandowontu | Star Fox | Action > Shooter | SNES | GP | Complete | 1.02 | 17 Dec 2021 |
| StarTropics - Refined Mike Sprite | TakuikaNinja | StarTropics | Role Playing > Action RPG | NES | G | Improvement | 1.0 | 28 Jan 2018 |
| StarTropics - No Movement Delay | Trisma | StarTropics | Role Playing > Action RPG | NES | GP | Improvement | 1.0 | 09 Feb 2017 |
| StarTropics - Mapper Fix | TakuikaNinja | StarTropics | Role Playing > Action RPG | NES | O | Bug Fix | 1.0 | 05 Jan 2020 |
| StarTropics (Music Fix) | rainwarrior | StarTropics | Role Playing > Action RPG | NES | S | Bug Fix | 1.0 | 19 Nov 2014 |
| StarTropics (MMC3) | tqhoang | StarTropics | Role Playing > Action RPG | NES | O | Bug Fix | 1.0 | 26 May 2020 |
| StarRevenge 0.5 - Unused Levels | BroDute | Super Mario 64 | Action > Platformer | N64 | G, L, T | Complete | 1.0.1b | 18 Apr 2014 |
| Starlight Mario | TPWC Hacks | Super Mario Bros. | Action > Platformer | NES | G, L, T, GP | Complete | 1.0a | 05 Jul 2020 |
