| Splatterhouse Chrome | guemmai | Splatterhouse | Action > Beat 'Em Up | TG16 | G, L, GP | Complete | 1.0 | 13 Jan 2009 |
| Splatterhouse 2 "classic mask" Rick and color hack | fusaru | Splatterhouse 2 | Action > Beat 'Em Up | GEN | G | Improvement | 1.00 | 16 Apr 2016 |
| SD Splatterhouse MMC-3 Hack | MottZilla | Splatterhouse: Wanpaku Graffiti | Action | NES | O | Improvement | 1.2 | 19 Jul 2008 |
| Spy Hunter CNROM to MMC3 Hack | infidelity | Spy Hunter | Racing | NES | O | Improvement | 1.0 | 30 Nov 2013 |
| Squashed Reversed | S. K. Dumbbus | Squashed | Action > Platformer | NES | G, T, GP | Improvement | 1.0 | 26 Apr 2013 |
| Mush Mush - Toad and Toadette | forgotusername | Squashed | Action > Platformer | NES | G, T | Complete | 1.0 | 02 Jul 2019 |
| Star Force - Title Mod | Makimura Manufacturing | Star Force | Action > Shooter | NES | G | Improvement | 1.0 | 08 Jun 2011 |
| Star Fox 2 - 52MHz Overclockable | The Real Phoenix | Star Fox 2 | Action > Shooter | SNES | O | Improvement | 1.0 | 21 Oct 2017 |
| Star Ocean no S-DD1/96Mbit hack | Neviksti | Star Ocean | Role Playing | SNES | O | Improvement | 1.0 | 13 Jul 2004 |
| Star Ocean: First Departure Difficulties | Tzepish | Star Ocean: First Departure | Role Playing | PSP | GP | Improvement | 1.05 | 29 Mar 2009 |
| Star Soldier Laser Hack | Guyver (X.B.M.) | Star Soldier | Action > Shooter | NES | G, GP | Improvement | 1.0 | 07 Oct 2017 |
| Star Soldier Vanishing Earth (Aleck64) Retail N64 Patch | Zoinkity | Star Soldier: Vanishing Earth | Action > Shooter | N64 | O | Improvement | 1.0 | 04 Jan 2015 |
| Star Wars Easy | chronix | Star Wars (JVC) | Action > Platformer | NES | GP | Improvement | 1.0 | 04 Nov 2018 |
| Star Wars - The Empire Strikes Back Easy | chronix | Star Wars: The Empire Strikes Back | Action > Platformer | NES | GP | Improvement | 1.0 | 10 Feb 2019 |
| StarTropics (Music Fix) | rainwarrior | StarTropics | Role Playing > Action RPG | NES | S | Bug Fix | 1.0 | 19 Nov 2014 |
| StarTropics - No Movement Delay | Trisma | StarTropics | Role Playing > Action RPG | NES | GP | Improvement | 1.0 | 09 Feb 2017 |
| StarTropics - Refined Mike Sprite | TakuikaNinja | StarTropics | Role Playing > Action RPG | NES | G | Improvement | 1.0 | 28 Jan 2018 |
| STED Experience | KingMike's Translations | STED: Iseki Wakusei no Yabou | Role Playing | NES | GP | Improvement | 1.0 | 11 Apr 2007 |
| Sted Easy | ded302 | STED: Iseki Wakusei no Yabou | Role Playing | NES | GP | Improvement | 1.0 | 02 Jul 2007 |
| Stormlord Decensored Hack | Fargoth | Stormlord | Action > Platformer | GEN | G | Improvement | 0.80 | 05 Mar 2007 |
