| Boat-Race | Inventor | F-1 Race | Racing | NES | G | Complete | 1.0 | 01 Jan 2001 |
| Exodus (Redesign) | Immutable | Exodus: Journey to the Promised Land | Puzzle | NES | G, T, O | Improvement | 7.1 | 29 Jan 2018 |
| Exile Font Hack | belthegor | Exile | Role Playing | GEN | T | Improvement | 1.01 | 23 Feb 2021 |
| Risker | Inventor | Excitebike | Racing | NES | G | Improvement | 1.0 | 01 Jan 2001 |
| Skeleton Bike | SPOOKY KIDS hack posse | Excitebike | Racing | NES | G, T | Improvement | 1.0 | 22 Oct 1998 |
| Excitebike w/ SRAM + MMC1 Mapper | Morgan Johansson | Excitebike | Racing | NES | O | Improvement | 1.0b | 01 Apr 2013 |
| Excitebike NROM to MMC3 Hack | infidelity | Excitebike | Racing | NES | O | Improvement | 1.0 | 03 Dec 2013 |
| Demonbike 2 | DANGER X | Excitebike | Racing | NES | G, L, GP | Complete | 1.0 | 29 Jan 2016 |
| Mario Bike | kmbTos | Excitebike | Racing | NES | G, T | Improvement | 1.0 | 03 Jun 2020 |
| Excitebike MMC5 Patch+Compact-Mapper | Dracula X | Excitebike | Racing | NES | O | Improvement | 1.1 | 02 May 2022 |
| Evolution Worlds - Undub | CDRomance | Evolution Worlds | Role Playing | GC | S | Improvement | 1.0 | 08 Apr 2022 |
| EC CD AI Nerf | BillyTime! Games | Eternal Champions - Challenge From The Dark Side | Action > Fighting | SegaCD | GP | Improvement | 2.0 | 05 Jul 2020 |
| Eternal Champions - Special Edition | BillyTime! Games | Eternal Champions | Action > Fighting | GEN | GP | Improvement | 2.3 | 28 Jul 2020 |
| Eientei Action | DASTARD | Elevator Action | Action | NES | G, T | Improvement | 1.0 | 01 Nov 2007 |
| El Viento Enhancement | Jon Najar | El Viento | Action > Platformer | GEN | G, S, T | Bug Fix | 101010 | 10 Oct 2010 |
| Eien Land: Meikyuu no Fukkoku | DASTARD | Eggerland: Meikyuu no Fukkatsu | Puzzle | NES | G | Improvement | 1.0 | 01 Jan 2010 |
| Eek! The Cat - Color Enhancement | Mister Man | Eek! The Cat | Action > Platformer | SNES | G | Improvement | 1.0 | 16 Nov 2021 |
| Ecco The Dolphin SRAM | BillyTime! Games | Ecco the Dolphin | Action Adventure | GEN | O | Improvement | 1.1 | 27 Apr 2021 |
| Earth Worm Jim 3 ENHANCED COLOR | sebastianangel | Earthworm Jim 3 | Action > Platformer | NES | G | Improvement | 1.1 | 28 Sep 2020 |
| Earthworm Jim 2 weapon select mod | Nemesis_c | Earthworm Jim 2 | Action > Platformer | GEN | GP | Improvement | 1.0 | 04 Aug 2013 |
