| SSF2T/X Revival: Akuma/Gouki CPU Color Fix | RealGaea | Super Street Fighter II Turbo Revival | Action > Fighting | GBA | G | Improvement | 1.0 | 07 Jul 2017 |
| SRW4 - from Pacific rim | Gigan | Dai-4-Ji Super Robot Taisen | Strategy > Turn Based | SNES | G, T | Complete | 1.0 | 10 Nov 2019 |
| SRW4 - from N64 charactor | Gigan | Dai-4-Ji Super Robot Taisen | Strategy > Turn Based | SNES | G, T | Complete | 1.0 | 09 Nov 2019 |
| SrBehemoth Fix | Dragonsbrethren | Final Fantasy III | Role Playing | SNES | GP | Bug Fix | 1.1 | 22 Aug 2008 |
| Squeaky Clean Adventure | Polargames | Kirby's Adventure | Action > Platformer | NES | G, L | Improvement | 1.5 | 22 Jul 2019 |
| Squashed Reversed | S. K. Dumbbus | Squashed | Action > Platformer | NES | G, T, GP | Improvement | 1.0 | 26 Apr 2013 |
| Spy Hunter CNROM to MMC3 Hack | infidelity | Spy Hunter | Racing | NES | O | Improvement | 1.0 | 30 Nov 2013 |
| Spudd - The Journey Home | Montagna | Super Mario Bros. | Action > Platformer | NES | G, L | Complete | 1.0 | 01 Jan 2000 |
| Splatterhouse Chrome | guemmai | Splatterhouse | Action > Beat 'Em Up | TG16 | G, L, GP | Complete | 1.0 | 13 Jan 2009 |
| Splatterhouse 2 "classic mask" Rick and color hack | fusaru | Splatterhouse 2 | Action > Beat 'Em Up | GEN | G | Improvement | 1.00 | 16 Apr 2016 |
| Spirit bug fix | Gemini | Final Fantasy VII | Role Playing | PSX | GP | Bug Fix | 1.0 | 09 Jan 2009 |
| Spiny Egg Behavior Fix for SMB1 and Lost Levels | ZeroShift | Super Mario All-Stars | Action > Platformer | SNES | GP | Bug Fix | 1.1 | 12 Dec 2016 |
| Spider-Man: Return of the Sinister Six color fix | wolfamancer97 | Spider-Man: Return of the Sinister Six | Action > Platformer | NES | G, O | Improvement | final | 05 Apr 2019 |
| Spider Wars | TLT | Battle City | Action | NES | G, L | Complete | 1.0 | 01 Jan 2011 |
| Spelunker Yukkuri | DASTARD | Spelunker | Action > Platformer | NES | G | Improvement | 1.0 | 01 Feb 2009 |
| Spellcaster - SRAM save | Ichigobankai | Spellcaster | Role Playing > Action RPG | SMS | O | Improvement | 1.0 | 20 Aug 2017 |
| Spell Name Update | Almagest | Breath of Fire III | Role Playing | PSX | T | Improvement | 1.0 | 26 Sep 2016 |
| Spell Name Modernization Patch | Reiska | Dragon Warrior III | Role Playing | NES | T | Improvement | 1.1 | 16 May 2012 |
| Spekkio Lufia | Artemis | Lufia II: Rise of the Sinistrals | Role Playing | SNES | G, T, GP, O | Improvement | 4.7 | 10 Sep 2019 |
| Speedy Gonzales - Level 6-1 bugfix | sluffy | Speedy Gonzales in Los Gatos Bandidos | Action > Platformer | SNES | O | Bug Fix | 20181102 | 11 Feb 2018 |
