| Oh Shit | Oh No! | Aackosoft | 1985 | Action | MSX | N | N | Y | N |
| Ogre Battle: The March of the Black Queen | Densetsu no Ogre Battle: The March of the Black Queen | Enix | 12 March 1993 | Strategy > Turn Based | SNES | Y | Y | Y | Y |
| Ogre Battle 64: Person of Lordly Caliber | No Alternate Title | Nintendo | 14 July 1999 | Strategy > Turn Based | N64 | N | N | N | Y |
| Oda Nobunaga Den | No Alternate Title | Koei | 23 September 1998 | Strategy > Turn Based | PSX | N | N | Y | N |
| O.D.T. | O.D.T.: Escape… Or Die Trying | Infogrames | 1999 | Action | N64 | N | Y | N | N |
| Nyorols | No Alternate Title | MIA | 1983 | Action | MSX | N | N | Y | N |
| Nuts & Milk | No Alternate Title | Hudson | 21 July 1984 | Action | NES | Y | Y | Y | Y |
| Nushi Tsuri Adventure: Kite no Bouken | Fishing King Adventure: Kite's Adventure | Victor Interactive | 04 August 2000 | Role Playing | GB | N | Y | Y | N |
| Nostalgia | Nostalgeo no Kaze | Tecmo | 06 November 2008 | Role Playing | NDS | N | N | Y | N |
| North and South | North & South - Wakuwaku Nanboku Sensou | Kemco | 21 September 1990 | Strategy | NES | N | N | Y | N |
| Noobow | No Alternate Title | Irem | 11 December 1992 | Action > Platformer | GB | N | N | Y | N |
| Nobunaga no Yabou: Game Boy Ban 2 | Nobunaga's Ambition: Game Boy Version 2 | Koei | 02 April 1999 | Strategy | GB | N | N | Y | N |
| Nishijin Pachinko Monogatari 2 | Nishijin Pachinko 2 | KSS | 28 June 1996 | Other | SNES | N | N | Y | N |
| Nishijin Pachinko 3 | No Alternate Title | KSS | 20 December 1996 | Other | SNES | N | N | Y | N |
| Nintendo World Cup | Nekketsu Koukou Dodgeball Bu: Soccer Hen | Technos | 18 May 1990 | Sports | NES | Y | N | Y | Y |
| Nintendo World Cup | Nekketsu Koukou Soccer-Bu: World Cup Hen | Nintendo | June 1991 | Sports | GB | N | N | Y | N |
| Ninpen Manmaru | No Alternate Title | Enix | 18 December 1997 | Action > Platformer | SAT | N | N | Y | N |
| Ninku | No Alternate Title | Sega | 21 July 1995 | Action > Fighting | GG | N | N | Y | N |
| Ninjara Hoi! | Ninja Rahoi! | ASCII | 08 August 1990 | Role Playing | NES | N | N | Y | N |
| Ninja-Kun: Ashura no Shou | Ninja Boy 2 | UPL | 27 May 1988 | Action > Platformer | NES | N | N | Y | N |
