Like I said, I don't know where I'm going with this... I might make some second-gen cards, no guarantees, but keep in mind I'm a lousy artist... as far as I know.
Unfortunately a card can have only 2 attacks including pokemon powers, so I'd have to remove one of ho-oh's attacks. Other than that it should be quite doable.
But the mewtwos? I could only make a rough approximation of them. Clearly they reference a lot of elements not in the game, such as burn status and steel type. I'd be more interested in making real, balanced cards - that Mecha Mewtwo is the most overpowered card I've ever seen... just saying.