| Shikinjou | Suicidal Translations | Puzzle | NES | Fully Playable | 1.00 | 03 Sep 2001 | EN |
| Shikigami no Shiro | iwakura.productions | Action > Shooter | PC | Fully Playable | 1.0 | 22 Jun 2017 | EN |
| Sherlock Holmes: Hakushaku Reijou Yuukai Jiken | Psyklax | Action > Platformer | NES | Fully Playable | 1.1 | 09 Dec 2018 | EN |
| Shatterhand | Aeon Genesis | Action > Platformer | NES | Fully Playable | 1.01 | 05 Aug 2000 | EN |
| Shatterhand | chronix | Action > Platformer | NES | Fully Playable | 1.0 | 02 Feb 2019 | EN |
| Shanghai | Dave Shadoff | Puzzle | TG16 | Fully Playable | 0.99 | 13 Feb 2002 | EN |
| Shalom: Knightmare III | SLotman | Role Playing | MSX | Fully Playable | Beta 4 | 12 Dec 2003 | EN |
| Shadow Tower: Abyss | Mord of Swoonlight | Action Adventure | PS2 | Fully Playable | 1.0 | 28 Nov 2011 | EN |
| Shadow Brain | Stardust Crusaders, aishsha | Role Playing | NES | Fully Playable | 1.0 | 28 Apr 2016 | EN |
| Shadow Brain | MrRichard999 | Role Playing | NES | Addendum | 1.0 | 28 Apr 2016 | EN |
| Seven Mansions: Ghastly Smile | ArcaneAria | Action > Shooter | DC | Fully Playable | 1.3 | 14 Dec 2020 | EN |
| Senjou no Valkyria 3: Extra Edition | Valkyria Chronicles 3 Translation Project | Strategy > Turn Based | PSP | Unfinished | Patch 2 | 06 Jan 2014 | EN |
| Sengoku Denshou | Vice Translations | Action > Beat 'Em Up | SNES | Fully Playable | 1.00 | 28 Jun 2012 | EN |
| Seirei Gari | snark | Adventure | NES | Fully Playable | 1.0 | 19 May 2007 | EN |
| Seirei Gari | Proveaux | Adventure | NES | Addendum | 1.0 | 10 Feb 2013 | EN |
| Seiko-Chan SOS | Takechi | Action > Shooter | PC88 | Fully Playable | 1.0 | 31 Jan 2011 | EN |
| Seiken Psycho Caliber: Maju no Mori Densetsu | The Spoony Bard | Role Playing > Action RPG | FDS | Fully Playable | 1.0 | 20 Dec 2000 | EN |
| Seiken Densetsu 3 | LNF Translations, Neill Corlett, SoM2Freak | Role Playing > Action RPG | SNES | Fully Playable | 1.01 | 27 Aug 2000 | EN |
| Secret of Mana | The SAP Team | Role Playing > Action RPG | SNES | Fully Playable | 1.8 | 04 Jan 2021 | EN |
| SD The Great Battle: Aratanaru Chousen | Aeon Genesis | Action | SNES | Fully Playable | 1.0 | 07 Mar 2018 | EN |
