| Dr. Lip | Midna | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 02 Jun 2013 |
| Dr. Luigi | Shugo | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 05 Jan 2014 |
| Dr. Mario - Crystal Clear | Tempes | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 01 Jan 1999 |
| Dr. Pinkie | SnivianMoon | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 01 Jan 1999 |
| Dr. Mario - MMC1 to MMC3 | infidelity | Dr. Mario | Puzzle | NES | O | Improvement | 1.0 | 15 Nov 2013 |
| Dr. Alex | Prince Manic | Dr. Mario | Puzzle | NES | G | Improvement | 1.0.8 | 19 Jul 2017 |
| Dr. Mario - 2 Players Inverse Hack | San Marino | Dr. Mario | Puzzle | NES | GP | Improvement | 1.0 | 03 Apr 2016 |
| Dr. Mario NES - no punish | Nesrocks | Dr. Mario | Puzzle | NES | GP | Improvement | 0.1 | 19 Feb 2017 |
| Dr. Mario Gameboy - no punish | rainponcho | Dr. Mario | Puzzle | GB | GP | Improvement | 0.1 | 21 Feb 2017 |
| Dr. Dadio | Dr. Dadio | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 14 Jan 2007 |
| Dr. Mario Black and White TV | mr-volk | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 11 Jan 2018 |
| Dr. Mario - Renewed | JY | Dr. Mario | Puzzle | GB | G | Improvement | 1.0 | 31 Oct 2018 |
| Dr. Bowsette/Dr. Boosette | Kazufox | Dr. Mario | Puzzle | NES | G, T | Improvement | 1.0 | 23 Nov 2019 |
| Dr. Mario DX | marc_max | Dr. Mario | Puzzle | GB | G, O | Improvement | 1.0 | 20 Jul 2020 |
| Dr. Garfield | Pangent Technologies | Dr. Mario | Puzzle | NES | G, S, T, GP, O | Improvement | 19 | 23 Nov 2020 |
| Dr. Garfield (GB/GBC) | Pangent Technologies | Dr. Mario | Puzzle | GB | G | Improvement | 2.0 | 19 Nov 2020 |
| Colorblind Dr. Mario | TheKMan | Dr. Mario | Puzzle | NES | G | Improvement | 1.0 | 30 Dec 2020 |
| Dr. Robotnik's Mean Bean Machine - DX Edition | RadioTails | Dr. Robotnik's Mean Bean Machine | Puzzle | GEN | G, S, T, O | Improvement | 3.1 | 28 Dec 2020 |
| Dr. Robotnik's MBM - 4 Colors for Battle | ONLYUSEmeFEET | Dr. Robotnik's Mean Bean Machine | Puzzle | GEN | G, GP | Improvement | 1.0 | 30 Sep 2020 |
| Dragon Ball Z Anime Colors | KanonZombie | Dragon Ball Z: Buyuu Retsuden | Action > Fighting | GEN | G | Improvement | 1.0 | 05 Jul 2020 |
